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En protokol for Computer-Based proteiners struktur og funktion Prediction
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En protokol for Computer-Based proteiners struktur og funktion Prediction

Article DOI: 10.3791/3259-v • 16:41 min • November 3rd, 2011
November 3rd, 2011 •
1,2, 1, 1, 1,2
1Center for Computational Medicine and Bioinformatics, University of Michigan, 2Center for Bioinformatics and Department of Molecular Bioscience, University of Kansas

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Retningslinjer for computerbaseret strukturelle og funktionelle karakterisering af protein ved hjælp af I-TASSER rørledningen er beskrevet. Fra forespørgsel protein sekvens, er 3D-modeller genereret ved hjælp af flere tråde alignments og iterativ strukturelle samling simuleringer. Funktionelle slutninger er derefter trukket baseret på kampe til proteiner med kendt struktur og funktioner.

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Biokemi On-line server I-TASSER protein struktur forudsigelse funktion forudsigelse
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