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Implantação de um Cuff Carotid para Triggering Shear-estresse aterosclerose induzida em camundongos
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Implantação de um Cuff Carotid para Triggering Shear-estresse aterosclerose induzida em camundongos

Article DOI: 10.3791/3308-v • 07:52 min • January 13th, 2012
January 13th, 2012 •
1, 2,3, 1, 3, 2, 4, 4, 1, 1
1European Institute for Molecular Imaging, Westfälische Wilhelms-University Münster, 2British Heart Foundation Cardiovascular Sciences Unit, Imperial College London, 3Department of Bioengineering, Imperial College London, 4Biomedical Engineering, Eindhoven University of Technology

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O manguito constricting apresentado neste artigo é projetado para induzir a aterosclerose na artéria carótida comum murino. Devido à forma cônica de sua luz interior do manguito implantado gera regiões bem definidas de baixa, alta tensão e de cisalhamento oscilatório desencadear o desenvolvimento de lesões ateroscleróticas de diferentes fenótipos inflamatórios.

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Medicina aterosclerose mouse doenças cardiovasculares tensão de cisalhamento
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