Name: Assaying the Kinase Activity of LRRK2 in vitro
Uploaded: 2018-02-17T09:46:54-05:00
Duration: 6 min 10 s
Description: Leucine Rich Repeat Kinase 2 (LRRK2) is a 2527 amino acid member of the ROCO family of proteins, possessing a complex, multidomain structure including a GTPase domain (termed ROC, for Ras of Complex proteins) and a kinase domain1.

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含量测定的LRRK2的激酶活性在体外

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含量测定的LRRK2的激酶活性在体外
Article DOI: 10.3791/3495-v • 06:10 min • January 18th, 2012
January 18th, 2012 •

Patrick A. Lewis¹

¹Department of Molecular Neuroscience, UCL Institute of Neurology

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富亮氨酸重复激酶2是一个大型的多域激酶，基因突变，其中最常见的帕金森氏病的遗传原因。这种蛋白激酶活性分析已被证明是在了解这种蛋白质的生物学和功能障碍的重要工具。在本文中，

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分子生物学，59期激酶，LRRK2，帕金森氏症

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含量测定的LRRK2的激酶活性在体外

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