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Journal / Bioengineering / Gene Levering og transfektion i Human…
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Bioengineering

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JoVE Journal Bioengineering
Gene Levering og transfektion i Human bugspytkirtelkræftceller hjælp epidermal vækstfaktor receptor-målrettede Gelatine-baseret Engineered Nanovectors
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Gene Levering og transfektion i Human bugspytkirtelkræftceller hjælp epidermal vækstfaktor receptor-målrettede Gelatine-baseret Engineered Nanovectors

Article DOI: 10.3791/3612-v • 08:35 min • January 4th, 2012
January 4th, 2012 •
1, 1
1Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University

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Type B gelatine-baserede manipuleret nanovectors system (gensen) blev udviklet til systemisk gen levering og transfektion i behandlingen af ​​kræft i bugspytkirtlen. Ved ændring med epidermal vækstfaktor receptor (EGFR) specifikke peptid på overfladen af ​​nanparticles, kunne de mål på EGFR receptor og frigivelse plasmid under reducerende miljø, såsom høj intracellulær glutathion koncentrationer.

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Bioteknik Gelatine Nanopartikel genterapi målrettet Levering kræft i bugspytkirtlen
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