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Immunology and Infection

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JoVE Journal Immunology and Infection
Vurdere Nedsatt Metabolske endringer under Progressive Colonization of Germ-free Mouse av 1 H NMR spektroskopi
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Vurdere Nedsatt Metabolske endringer under Progressive Colonization of Germ-free Mouse av 1 H NMR spektroskopi

Article DOI: 10.3791/3642-v • 07:54 min • December 15th, 2011
December 15th, 2011 •
1, 2
1School of Chemistry, Food and Pharmacy, The University of Reading, 2Department of Nutritional Sciences, The University of Reading

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En progressiv kolonisering prosedyren er beskrevet å vurdere nærmere dens innvirkning på verten hepatisk metabolisme. Colonization er overvåket non invasiv ved å evaluere urinutskillelse av mikrobiell co-metabolitter av NMR-baserte metabolske profilering mens hepatisk metabolisme er vurdert av High Resolution Magisk Angle Spinning (HR MAS) NMR profilering av intakt biopsi.

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Immunologi Germ-free dyr kolonisering NMR HR MAS NMR metabonomics
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