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JoVE Journal
Immunology and Infection

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Article DOI: 10.3791/3905-v 09:58 min June 5th, 2012
June 5th, 2012

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Summary

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Schistosoma mansoni-æg er potente stimulatorer af T-hjælpercelle type 2 (Th2) immunrespons, der er karakteristisk for parasit-infektion, astma og allergisk inflammation. Denne protokol anvender S. mansoni æg injektion til frembringelse af en CD4 Th2 cytokin-induceret inflammatorisk respons i lungerne, kendetegnet ved lunge granulomdannelse omkring ægget, eosinofili og makrofag alternativ aktivering.

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Immunologi Infection Microbiology helminther parasit en mus Th2- lunge- inflammation granulom alternativ aktivering makrofag
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