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Funktionel Neuroimaging Med Ultrasonic blod-hjerne barrieren forstyrrelser og mangan-forstærket MRI
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Funktionel Neuroimaging Med Ultrasonic blod-hjerne barrieren forstyrrelser og mangan-forstærket MRI

Article DOI: 10.3791/4055-v • 08:36 min • July 12th, 2012
July 12th, 2012 •
1, 2, 3, 3, 2
1Department of Radiology, Stanford University, 2Center for In Vivo Microscopy, Duke University Medical Center, 3Department of Biomedical Engineering, Duke University

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En teknik er beskrevet for bredt åbning af blod-hjerne-barrieren hos mus ved hjælp af mikrobobler og ultralyd. Anvendelse af denne teknik, kan mangan indgives til musehjerne. Fordi mangan er en MRI-kontrastmiddel, der ophobes i depolariserede neuroner, denne tilgang gør det muligt billeder af neuronal aktivitet.

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Neuroscience Molecular Biology Biomedical Engineering mus ultralyd blod-hjerne-barrieren funktionel MRI fMRI mangan-forstærket MRI MEMRI
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