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Journal / Medicine / A coloração imuno-histoquímica de B7-H1 (PD-L1)…
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A coloração imuno-histoquímica de B7-H1 (PD-L1) na histológicos em parafina lâminas de tecido adenocarcinoma do pâncreas
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A coloração imuno-histoquímica de B7-H1 (PD-L1) na histológicos em parafina lâminas de tecido adenocarcinoma do pâncreas

Article DOI: 10.3791/4059-v • 10:11 min • January 3rd, 2013
January 3rd, 2013 •
1,2, 1,2, 1,2,3, 1, 1,2,4, 3,5, 6, 1,2,5,7,8, 1,2,5,8, 1,2,4,5,7
1The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 2Department of Oncology, The Johns Hopkins University School of Medicine, 3Department of Dermatology, The Johns Hopkins University School of Medicine, 4Department of Surgery, Johns Hopkins University School of Medicine, 5The Sol Goldman Pancreatic Cancer Center, The Johns Hopkins University School of Medicine, 6Yale Cancer Center, Yale School of Medicine, 7The Skip Viragh Center for Pancreatic Cancer, The Johns Hopkins University School of Medicine, 8Department of Pathology, The Johns Hopkins University School of Medicine

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B7-H1 (PD-L1) e a sua ligação ao PD-1 fornece um sinal induzida por tumor principal imunossupressor no microambiente do tumor. Uma técnica de coloração imuno-histoquímica para caracterizar a expressão e localização de B7-H1 em adenocarcinoma pancreático é descrito aqui.

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Biologia do Câncer Edição 71 Medicina Imunologia Bioquímica Biologia Molecular Biologia Celular Química Oncologia imuno-histoquímica B7-H1 (PD-L1) adenocarcinoma do pâncreas câncer de pâncreas pâncreas tumor a imunidade das células T o câncer
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