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Vurdere Replication og betacellefunksjon i Adenovirally-transduced Isolert gnager Holmer
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Vurdere Replication og betacellefunksjon i Adenovirally-transduced Isolert gnager Holmer

Article DOI: 10.3791/4080-v • 09:31 min • June 25th, 2012
June 25th, 2012 •
1,2, 2, 2, 1,2
1Department of Pediatrics, Indiana University School of Medicine, 2Department of Cellular & Integrative Physiology, Indiana University School of Medicine

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Denne protokollen gjør det mulig å identifisere faktorer som modulerer funksjonell beta cellemasse å finne potensielle terapeutiske mål for behandling av diabetes. Protokollen består av en strømlinjeformet metode for å vurdere holmen replikering og betacellefunksjon i isolerte rotte holmer etter manipulering av genuttrykk med adenoviruses.

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Medisin fysiologi beta celle genekspresjon holme diabetes insulin sekresjon spredning adenovirus rotte
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