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Immunology and Infection

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JoVE Journal Immunology and Infection
Påvisning av MicroRNAs i microglia av Real-time PCR i Normale CNS og under Neuroinflammation
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Påvisning av MicroRNAs i microglia av Real-time PCR i Normale CNS og under Neuroinflammation

Article DOI: 10.3791/4097-v • 13:45 min • July 23rd, 2012
July 23rd, 2012 •
1, 1, 1, 1
1Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School

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Microglia er bosatt makrofager som gir den første linjen i forsvaret og immun overvåking av det sentrale nervesystemet. MicroRNAs er regulatoriske molekyler som spiller en viktig rolle i mange fysiologiske prosesser deriblant aktivering og differensiering av makrofager. I denne artikkelen beskriver vi metoden for måling av microRNAs i microglia.

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Immunologi nevrovitenskap genetikk microglia makrofager mikroRNA hjerne mus real-time PCR neuroinflammation
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