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JoVE Journal
Immunology and Infection
Author Produced

This content is Open Access.

Reverse Genetics Mediated Recovery of Infectious Murine Norovirus
 
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Reverse Genetics Mediated Recovery of Infectious Murine Norovirus

Article DOI: 10.3791/4145-v 13:48 min June 24th, 2012
June 24th, 2012

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Summary

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Click here for the English version.

Noroviruses are a major cause of gastroenteritis yet molecular techniques for their characterisation are still relatively new. Here we report two different reverse genetics approaches for the efficient recovery of murine norovirus (MNV), the only member of this genus which can be propagated in cell culture.

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Reverse Genetics Recovery Infectious Murine Norovirus Human Noroviruses Gastroenteritis Outbreaks Hospitals Antiviral Approaches Cell Culture Propagation Genomic RNA Molecules Open Reading Frames (ORFs) Non-structural Proteins Capsid Proteins Virulence Factor (VF1)
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