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High-throughput screening para pequenas moléculas Moduladores de canais de potássio Interiores retificador
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High-throughput screening para pequenas moléculas Moduladores de canais de potássio Interiores retificador

Article DOI: 10.3791/4209-v • 10:07 min • January 27th, 2013
January 27th, 2013 •
1,2, 1,3, 1,2
1Department of Pharmacology, Vanderbilt University School of Medicine, 2Department of Anesthesiology, Vanderbilt University School of Medicine, 3Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine

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Os métodos para o desenvolvimento e validação de um ensaio quantitativo de fluorescência para medir a actividade de potássio rectificador de entrada (Kir) canais de rastreio de alto rendimento composto é apresentado.

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Bioquímica Edição 71 Biologia Molecular Química Biologia Celular Química Biologia Farmacologia Farmacologia Molecular canais de potássio descoberta de medicamentos triagem de drogas de alto rendimento pequenas moléculas o fluxo a fluorescência de tálio análise de xadrez DMSO linhas celulares ensaio tela
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