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Journal / Immunology and Infection / Utarbeidelse av Tumor Antigen-lastet Moden…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Utarbeidelse av Tumor Antigen-lastet Moden dendrittiske celler for Immunterapi
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Utarbeidelse av Tumor Antigen-lastet Moden dendrittiske celler for Immunterapi

Article DOI: 10.3791/50085-v • 08:40 min • August 1st, 2013
August 1st, 2013 •
1, 2, 1, 1, 1, 1
1Cancer Institute, NYU Langone Medical Center, 2Infectious Diseases, NYU Langone Medical Center

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Den mest benyttede metode for generering av et stort antall autologe dendrittiske celler (DC) for anvendelse i tumor immunoterapi er beskrevet. Metoden bruker IL-4 og GM-CSF for å skille DCs fra monocytter. Umodne DC blir stimulert til å modne og deretter lastet med antigener før de blir injisert tilbake i pasienten.

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Cancer Biology medisin immunologi molekylærbiologi cellebiologi Biomedical Engineering anatomi fysiologi dendrittiske celler Immunterapi dendrittiske celler immunterapi vaksine celle isolasjon flowcytometri cellekultur kliniske teknikker
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