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Immunology and Infection

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Fremstilling af tumorantigen-loaded dendritiske celler til immunterapi
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Fremstilling af tumorantigen-loaded dendritiske celler til immunterapi

Article DOI: 10.3791/50085-v • 08:40 min • August 1st, 2013
August 1st, 2013 •
1, 2, 1, 1, 1, 1
1Cancer Institute, NYU Langone Medical Center, 2Infectious Diseases, NYU Langone Medical Center

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Den mest almindeligt anvendte metode til at generere mange autologe dendritiske celler (DC'er) til anvendelse i tumor immunterapi er beskrevet. Fremgangsmåden anvender IL-4 og GM-CSF at differentiere udviklingslandene fra monocytter. De umodne DC'er stimuleres til modne og derefter fyldt med antigener, før de injiceres tilbage i patienten.

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Cancer Biology Lægevidenskab Immunologi Molekylærbiologisk Institut cellebiologi Biomedical Engineering anatomi fysiologi dendritiske celler Immunterapi dendritiske celler immunterapi vaccine celle isolation flowcytometri cellekultur kliniske teknikker
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