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JoVE Journal Neuroscience
Recording and Analysis of Circadian Rhythms in Running-wheel Activity in Rodents
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Recording and Analysis of Circadian Rhythms in Running-wheel Activity in Rodents

Article DOI: 10.3791/50186-v • 05:46 min • January 24th, 2013
January 24th, 2013 •
1, 2, 2
1Douglas Mental Health University Institute, Department of Psychiatry, McGill University, 2Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University

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Circadian rhythms in voluntary wheel-running activity in mammals are tightly coupled to the molecular oscillations of a master clock in the brain. As such, these daily rhythms in behavior can be used to study the influence of genetic, pharmacological, and environmental factors on the functioning of this circadian clock.

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Circadian Rhythms Running-wheel Activity Rodents Recording Analysis Voluntary Use Master Circadian Clock Suprachiasmatic Nucleus (SCN) Hypothalamus Entrainment Environmental Light-dark Cycle (LD Cycle) Subjective Time-of-day Circadian Time (CT) Zeitgeber Time (ZT) Circadian Oscillators
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