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Whole-Body Nanoparticle Aerosol Inhalation Exposures

Article DOI: 10.3791/50263-v • 10:11 min • May 7th, 2013
May 7th, 2013 •
1,2, 3, 3, 3, 3, 1, 1,2, 1,2, 1,2, 1,2
1Department of Physiology and Pharmacology, School of Medicine, West Virginia University, 2Center for Cardiovascular and Respiratory Sciences, West Virginia University, 3National Institute for Occupational Safety and Health

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Summary
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A whole-body nanoparticle aerosol inhalation exposure facility was constructed for nano-sized titanium dioxide (TiO2) inhalation toxicology studies. This system provides nano-TiO2 aerosol test atmospheres that have: 1) a steady mass concentration; 2) a homogenous composition free of contaminants; and 3) a stable particle size distribution during aerosol generation.

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Nanoparticle Aerosol Inhalation Exposures Engineered Nano-materials (ENM) Nanoparticle Inhalation Toxicology Studies Aerosol Concentration Homogenous Composition Stable Size Distribution Aerosol Generators Nebulizers Fluidized Beds Venturi Aspirators Wright Dust Feed Whole-body Nanoparticle Aerosol Inhalation Exposure System Nano-TiO2 Inhalation Toxicology Studies Nano-TiO2 Aerosol Generator Whole-body Inhalation Exposure Chamber Monitor And Control System
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