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Journal / Behavior / Skapa dynamiska bilder av kortlivat Dopamin…
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Behavior

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JoVE Journal Behavior
Skapa dynamiska bilder av kortlivat Dopamin Fluktuationer med lp-ntPET
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Skapa dynamiska bilder av kortlivat Dopamin Fluktuationer med lp-ntPET: Dopamin Filmer av cigarettrökning

Article DOI: 10.3791/50358-v • 14:21 min • August 6th, 2013
August 6th, 2013 •
1,2,3,4, 1,3, 1,3,4, 3,4, 5, 6, 1,2,3
1Diagnostic Radiology, Yale University, 2Psychiatry, Yale University, 3Yale PET Center, Yale University, 4Biomedical Engineering, Yale University, 5Nuclear Medicine, Massachusetts General Hospital, 6Radiological Sciences, University of California, Irvine

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Vi presenterar en ny metod PET imaging för att fånga dopamin fluktuationer orsakade av cigarettrökning. Ämnen röka i PET-scannern. Dynamiska PET-bilder modelleras voxel-by-voxel i tid genom lp-ntPET, som innehåller en tidsvarierande dopamin sikt. Resultatet är "filmer" av dopamin fluktuationer i striatum under rökning.

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Beteende neurovetenskap neurobiologi molekylärbiologi medicinsk teknik medicin anatomi fysiologi bildbehandling datorstödd receptorer dopamin dopamin Funktionella Neuroimaging Bindning konkurrenskraftig matematisk modellering (systemanalys) Neurotransmission övergående dopamin frisättning PET modellering linjära tidsinvarianta rökning F-test ventral-striatum kliniska tekniker
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