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Immunology and Infection

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JoVE Journal Immunology and Infection
Accelerated Typ 1 Diabetes Induktion in Mäusen durch adoptiven Transfer von CD4 + T diabetogene Cells
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Accelerated Typ 1 Diabetes Induktion in Mäusen durch adoptiven Transfer von CD4 + T diabetogene Cells

Article DOI: 10.3791/50389-v • 06:27 min • May 6th, 2013
May 6th, 2013 •
1, 1
1Department of Microbiology & Immunology, Pennsylvania State University College of Medicine

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Wir bieten eine reproduzierbare Methode, um Typ-1-Diabetes (T1D) bei Mäusen innerhalb von zwei Wochen zu induzieren durch den adoptiven Transfer von Insel-Antigen-spezifischen, primären CD4 + T-Zellen.

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Immunologie Medizin Zellbiologie Molekularbiologie Mikrobiologie Anatomie Physiologie Biomedizinische Technik Genetik Chirurgie Diabetes Typ 1 CD4 + T-Zellen diabetogene T-Zellen T-Zell-Transfer Diabetes Induktion Methode Diabetes T-Zellen Isolierung cell sorting FACS transgene Mäuse Tiermodell
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