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En modificeret Heterotop Svin Hind Limb Transplant Model for Translationel vaskulariserede Composite allotransplantation (VCA) Forskning
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En modificeret Heterotop Svin Hind Limb Transplant Model for Translationel vaskulariserede Composite allotransplantation (VCA) Forskning

Article DOI: 10.3791/50475-v • 09:09 min • October 14th, 2013
October 14th, 2013 •
1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
1Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine

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Vaskulariserede Composite Allotransplantations (VCA) er blevet en klinisk realitet. Dog er bred klinisk anvendelse af VCA begrænset af kronisk multi-drug immunosuppression. Forfatterne præsenterer en pålidelig og reproducerbar stor dyremodel til at oversætte nye immunomodulatoriske strategier, som kan minimere eller eventuelt eliminere behovet for immunsuppression VCA.

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Medicine øvre ekstremiteter Svin mikrokirurgi Tissue Transplantation Transplantation Immunology kirurgiske procedurer Operative vaskulariseret Composite Allotransplantater rekonstruktiv transplantation translationel forskning svin bagbenet allotransplantation knoglemarv osteomyocutaneous mikrovaskulære anastomose immunmodulation
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