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A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
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A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

Article DOI: 10.3791/50542-v • 05:51 min • May 6th, 2014
May 6th, 2014 •
*1, *1, 1, 1, 1, 2, 1, 3, 1, 1
1Department of Cardiology, University of Heidelberg, 2Department of Vascular Surgery, University of Heidelberg, 3Department of Cardiology, SLK Hospital am Plattenwald
* These authors contributed equally

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Summary
Automatic Translation

Atherosclerosis is a chronic inflammatory process. This manuscript illustrates an easy to use ex vivo model to investigate fresh carotid or coronary artery plaques. The ex vivo model allows for the investigation of potential substances on the inflammatory milieu in human atherosclerotic lesions and results can be analyzed by various methods.

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Atherosclerotic Plaque Model Lesion Biology Chronic Inflammatory Disease Vasculature Mouse Models Human Immune System In Vitro Cell Experiments Substance Of Interest Culture-dependent Variations Inflammatory Compound Atherosclerotic Lesions Plaque Culture Model Endarterectomy Coronary Artery Bypass Grafting RPMI Medium Cytokines Chemokines
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