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Immunology and Infection

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JoVE Journal Immunology and Infection
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Generazione di un nuovo vaccino a cellule dendritiche con melanoma e cellule staminali tumorali squamose

Article DOI: 10.3791/50561-v • 12:43 min • January 6th, 2014
January 6th, 2014 •
1, 1, 1, 1, 2, 3, 3, 3, 1, 2
1Department of Surgery, University of Michigan, 2Department of Internal Medicine, University of Michigan, 3Department of Otolaryngology, University of Michigan

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Valutato in ospiti immunocompetenti sigeneici, il vaccino a cellule dendritiche (DC) a base di cellule staminali tumorali (CSC) ha dimostrato un'immunità antitumorale significativamente più elevata rispetto ai tradizionali vaccini CC pulsati con cellule tumorali alla rinfusa eterogenee.

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Biologia del cancro Numero 83 Cellule staminali tumorali (CSC) Cellule Dendritiche (DC) Vaccino Immunoterapia del Cancro immunità antitumorale aldeide deidrogenasi
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