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Journal / Immunology and Infection / Génération d’un nouveau vaccin à cellules…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Génération d’un nouveau vaccin à cellules dendritiques utilisant des cellules souches de mélanome et de cancer malpighien
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Génération d’un nouveau vaccin à cellules dendritiques utilisant des cellules souches de mélanome et de cancer malpighien

Article DOI: 10.3791/50561-v • 12:43 min • January 6th, 2014
January 6th, 2014 •
1, 1, 1, 1, 2, 3, 3, 3, 1, 2
1Department of Surgery, University of Michigan, 2Department of Internal Medicine, University of Michigan, 3Department of Otolaryngology, University of Michigan

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Évalué chez des hôtes immunocompétents syngéniques, le vaccin à base de cellules dendritiques (DC) à base de cellules souches cancéreuses (CSC) a démontré une immunité antitumorale significativement plus élevée que les vaccins DC traditionnels pulsés avec des cellules tumorales en vrac hétérogènes.

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Biologie du cancer Numéro 83 Cellules souches cancéreuses (CSC) Cellules dendritiques (DC) Vaccin Immunothérapie du cancer immunité antitumorale aldéhyde déshydrogénase
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