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A avaliação pré-clínica da tirosina quinase inibidores para o tratamento de leucemia aguda
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A avaliação pré-clínica da tirosina quinase inibidores para o tratamento de leucemia aguda

Article DOI: 10.3791/50720-v • 10:49 min • September 18th, 2013
September 18th, 2013 •
1,2, 1, 1, 1, 1
1Department of Pediatrics, University of Colorado Anschutz Medical Campus, 2Department of Bone Marrow Transplantation, University Hospital of Essen

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As tirosina quinases receptoras são ectopicamente expressa em muitos cancros e foram identificadas como alvos terapêuticos em leucemia aguda. Este manuscrito descreve uma estratégia eficaz para a avaliação pré-clínica de inibidores da tirosina cinase para o tratamento de leucemia aguda.

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Medicina Edição 79 leucemia Receptor Proteína Tirosina Quinases Molecular Targeted Therapy Therapeutics romance pequena molécula inibidora receptor tirosina quinase leucemia
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