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Immunology and Infection

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JoVE Journal Immunology and Infection
Isolierung und Differenzierung von Th17 Naive CD4-T-Lymphozyten
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Isolierung und Differenzierung von Th17 Naive CD4-T-Lymphozyten

Article DOI: 10.3791/50765-v • 12:59 min • September 26th, 2013
September 26th, 2013 •
*1, *1, 1, 1, 1
1Department of Microbiology and Cell Science, The University of Florida
* These authors contributed equally

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Mit Effektor-Funktionen deutlich von anderen T-Zell-Untergruppen, Th17-Zellen wurden zentral bei entzündlichen Autoimmunerkrankungen in Verbindung gebracht. Diese in vitro-Differenzierung Th17-Protokoll bietet die Möglichkeit, festzustellen, ob naiven CD4 +-T-Lymphozyten in Th17-Zellen zu differenzieren und ihre Rolle in der Autoimmun-und Wirtsantwort weiter zu prüfen.

Tags

Immunologie Zellbiologie Molekularbiologie Medizin Infektion Th17-Zellen IL-17 Th17 Differenzierung T-Zellen Autoimmunerkrankungen Zell Isolation Kultur
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