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Primaire orthotopische glioom xenograften recapituleren infiltratieve groei en isocitraat dehydrogenase I mutatie
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Primaire orthotopische glioom xenograften recapituleren infiltratieve groei en isocitraat dehydrogenase I mutatie

Article DOI: 10.3791/50865-v • 09:43 min • January 14th, 2014
January 14th, 2014 •
1, 1, 1, 1,2,3
1Department of Neurology, Vanderbilt University Medical Center, 2Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, 3Neurology Service, Veteran Affairs TVHS

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Kwaadaardige gliomen vormen een heterogene groep van zeer infiltratieve gliane neoplasmata met duidelijke klinische en moleculaire kenmerken. Primaire orthotopische xenograften heroveren de histopathologische en moleculaire kenmerken van kwaadaardige glioomsubtypes in preklinische diermodellen.

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Geneeskunde Glioma Maligne glioom primaire orthotopische xenograft isocitraat dehydrogenase
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