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Xenoinjertos de glioma ortotópico primario Recapitulan el crecimiento infiltrativo y la mutación de la isocitrato deshidrogenasa I
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Xenoinjertos de glioma ortotópico primario Recapitulan el crecimiento infiltrativo y la mutación de la isocitrato deshidrogenasa I

Article DOI: 10.3791/50865-v • 09:43 min • January 14th, 2014
January 14th, 2014 •
1, 1, 1, 1,2,3
1Department of Neurology, Vanderbilt University Medical Center, 2Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, 3Neurology Service, Veteran Affairs TVHS

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Las gliomas malas constituyen un grupo heterogéneo de neoplasmas glial altamente infiltrativos con las características clínicas y moleculares distintas. Los xenografts orthotopic primarios recapitulan las características histopatológicas y moleculares de los subtipos malos de la glioma en modelos animales preclínicos.

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Medicina Número 83 Glioma Glioma Maligno xenoinjerto ortotópico primario isocitrato deshidrogenasa
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