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JoVE Journal Medicine
Primer Ortotopik Glioma Xenografts Infiltratif Büyüme ve İsocitrat Dehidrogenaz I Mutasyonu Rekapitulate
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Primer Ortotopik Glioma Xenografts Infiltratif Büyüme ve İsocitrat Dehidrogenaz I Mutasyonu Rekapitulate

Article DOI: 10.3791/50865-v • 09:43 min • January 14th, 2014
January 14th, 2014 •
1, 1, 1, 1,2,3
1Department of Neurology, Vanderbilt University Medical Center, 2Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, 3Neurology Service, Veteran Affairs TVHS

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Malign gliomalar, farklı klinik ve moleküler özelliklere sahip heterojen bir yüksek infiltive glial neoplazm grubunu oluşturur. Primer ortotopik ksinograftlar preklinik hayvan modellerinde malign glioma alt tiplerinin histopatolojik ve moleküler özelliklerini rekapitulate eder.

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Tıp Sayı 83 Glioma Malign glioma primer ortotopik ksinograft izoitrat dehidrogenaz
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