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浸润性膀胱移行细胞癌中的完整的人MUC1转基因小鼠免疫诱导免疫治疗发展模型
 
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浸润性膀胱移行细胞癌中的完整的人MUC1转基因小鼠免疫诱导免疫治疗发展模型

Article DOI: 10.3791/50868-v 11:02 min October 30th, 2013
October 30th, 2013

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Summary

Please note that all translations are automatically generated.

Click here for the English version.

的N-丁基-N-(4 - 羟丁基)亚硝胺的人粘蛋白1(MUC1)测试的目的MUC1基因定向免疫治疗的转基因小鼠中诱导的膀胱癌模型的开发。施用MUC1的目标肽疫苗后,MUC1的细胞毒性T淋巴细胞反应证实,通过测定血清中的细胞因子水平和T细胞的比活性。

Tags

医药,80期,膀胱,动物,转基因,癌症疫苗,免疫,动物实验模型,肿瘤膀胱癌,C57BL / 6小鼠,MUC1,免疫治疗,临床前模型
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