Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Biology / Mouse Genome Engineering Bruke Designer nukleaser
JoVE Journal
Biology

This content is Open Access.

JoVE Journal Biology
Mouse Genome Engineering Bruke Designer nukleaser
Isolation of Labile Multi-protein Complexes by in vivo Controlled Cellular Cross-Linking and Immuno-magnetic Affinity Chromatography
Journal (Biology)
Isolation of Labile Multi-protein Complexes by in vivo Controlled Cellular Cross-Linking and Immuno-magnetic Affinity Chromatography
DNA-based Fish Species Identification Protocol
Journal (Biology)
DNA-based Fish Species Identification Protocol
 
Click here for the English version

Mouse Genome Engineering Bruke Designer nukleaser

Article DOI: 10.3791/50930-v • 12:04 min • April 2nd, 2014
April 2nd, 2014 •
1, 2, 2, 1
1Institute of Laboratory Animal Science, University of Zurich, 2Department of Genetics, Cell Biology & Development and Center for Genome Engineering, University of Minnesota

Chapters

Summary
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Designer nukleaser som sink finger nukleaser (ZFNs) og transkripsjons aktivator lignende effektor nukleaser (Talens) kan brukes til å endre genomet muse preimplantation embryoer ved å utløse både ikkehomologe ende bli (NHEJ) og homolog rekombinasjon (HR) trasé. Disse fremskrittene muliggjøre rask generasjon av mus med presise genetiske modifikasjoner.

Tags

Genetikk oocytter mikroinjeksjon Designer nukleaser ZFN TALEN Genome Engineering
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter