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De ChroP aanpak combineert chip en massaspectrometrie te ontleden Locus-specifieke Proteomic Landschappen van Chromatin
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De ChroP aanpak combineert chip en massaspectrometrie te ontleden Locus-specifieke Proteomic Landschappen van Chromatin

Article DOI: 10.3791/51220-v • 24:02 min • April 11th, 2014
April 11th, 2014 •
1, 1
1Department of Experimental Oncology, European Institute of Oncology

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Door de combinatie van inheemse en verknopen van chromatine immunoprecipitatie met een hoge-resolutie massaspectrometrie, ChroP benadering stelt aan de samengestelde proteomics architectuur van histonmodificaties, varianten en niet-histonic eiwitten synergizing op functioneel verschillende chromatinedomeinen ontleden.

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Biochemie chromatine histon post-translationele modificaties (hPTMs) epigenetica massaspectrometrie proteomics SILAC chromatine immunoprecipitatie histon-varianten chromatome hPTMs cross-gesprekken
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