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Journal / Bioengineering / 凝血因子VIII的脂质纳米管螺旋组织
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Bioengineering

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JoVE Journal Bioengineering
凝血因子VIII的脂质纳米管螺旋组织
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凝血因子VIII的脂质纳米管螺旋组织

Article DOI: 10.3791/51254-v • 12:24 min • June 3rd, 2014
June 3rd, 2014 •
*1, *1, 2,3, 1, 1,3
1Department of Neuroscience and Cell Biology, University of Texas Medical Branch, 2Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, 3Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch
* These authors contributed equally

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Summary
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我们提出了低温电子显微镜，脂质纳米技术和结构分析的组合应用，以解决两个高度同源的FVIII形式与膜结合的结构：人和猪。在我们研制的实验室，以螺旋状组织两个功能重组FVIII形式对带负电荷的脂质纳米管（LNT）的方法进行说明。

Tags

生物工程，第88期，低温电子显微镜，脂质纳米管，螺旋装配，膜结合的组织，凝血因子VIII
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