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Journal / Immunology and Infection / Myelin oligodendrocyte Glycoprotein (MOG
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Immunology and Infection

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JoVE Journal Immunology and Infection
Myelin oligodendrocyte Glycoprotein (MOG
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Myelin oligodendrocyte Glycoprotein (MOG

Article DOI: 10.3791/51275-v • 08:03 min • April 15th, 2014
April 15th, 2014 •
1,2, 1, 1, 1,3
1Department of Neurology, University of Münster, 2Interdisciplinary Center for Clinical Research (IZKF), Münster, 3Institute of Physiology – Neuropathophysiology, University of Münster

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Eksperimentell autoimmun encefalomyelitt (EAE) er en etablert dyremodell av multippel sklerose. C57BL / 6 mus immunisert med myelin oligodendrocyte glykoprotein (MOG) peptid 35-55 (MOG 35-55), noe som resulterer i en stigende slapp lammelse forårsaket av autoreaktive immunceller i sentralnervesystemet. Protokoller for sykdom induksjon og overvåking vil bli diskutert.

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Immunology eksperimentell autoimmun encefalomyelitt EAE multippel sklerose MS dyremodell Autoimmunity nevroinflammasjon sentralnervesystem pertussis
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