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Journal / Immunology and Infection / La mielina glicoproteína del oligodendrocito (MOG
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Immunology and Infection

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JoVE Journal Immunology and Infection
La mielina glicoproteína del oligodendrocito (MOG
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La mielina glicoproteína del oligodendrocito (MOG

Article DOI: 10.3791/51275-v • 08:03 min • April 15th, 2014
April 15th, 2014 •
1,2, 1, 1, 1,3
1Department of Neurology, University of Münster, 2Interdisciplinary Center for Clinical Research (IZKF), Münster, 3Institute of Physiology – Neuropathophysiology, University of Münster

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La encefalomielitis autoinmune experimental (EAE) es un modelo animal establecido de la esclerosis múltiple. C57BL / 6 ratones se inmunizan con mielina de oligodendrocitos glicoproteína (MOG) péptido 35-55 (MOG 35-55), dando como resultado una parálisis flácida ascendente causada por las células inmunes autorreactivas en el sistema nervioso central. Se discutirán Protocolos para la inducción de la enfermedad y el seguimiento.

Tags

Inmunología Número 86 la encefalomielitis autoinmune experimental la EAE la esclerosis múltiple MS modelo animal autoinmunidad la neuroinflamación sistema nervioso central la tos ferina
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