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Journal / Biology / Oprensning af cystisk fibrose Ledningsevne…
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Biology

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Oprensning af cystisk fibrose Ledningsevne regulator protein udtrykt i
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Oprensning af cystisk fibrose Ledningsevne regulator protein udtrykt i

Article DOI: 10.3791/51447-v • 15:12 min • May 10th, 2014
May 10th, 2014 •
1, 1, 1, 1
1Faculty of Life Sciences, University of Manchester

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Heterolog ekspression og oprensning af cystisk fibrose transmembran konduktans regulator (CFTR) er betydelige udfordringer og begrænsende faktorer i udviklingen af ​​lægemiddelbehandlinger for cystisk fibrose. Denne protokol beskriver to metoder til isolering af milligram mængder af CFTR egnet til funktionelle og strukturelle studier.

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Biochemistry membranprotein cystisk fibrose CFTR ABCC7 proteinoprensning cystisk fibrose Foundation grønt fluorescerende protein
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