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Journal / Immunology and Infection / En metod för att generera Pulmonell neutrofili…
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Immunology and Infection

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JoVE Journal Immunology and Infection
En metod för att generera Pulmonell neutrofili Använda aerosoliserad Lipopolysackarid
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En metod för att generera Pulmonell neutrofili Använda aerosoliserad Lipopolysackarid

Article DOI: 10.3791/51470-v • 08:33 min • December 15th, 2014
December 15th, 2014 •
1, 1, 1, 1, 1,2
1Department of Medicine, Solna and CMM, Respiratory Medicine Unit, Karolinska Institutet, 2Safety Science, Global Regulator Affairs & Patient Safety, AstraZeneca Global Medicines Development

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Vi beskriver en metod för att inducera neutrofil pulmonell inflammation genom utmaning för aerosoliserad lipopolysackarid genom nebulisering, att modellera akut lungskada. Dessutom är grundläggande kirurgiska tekniker för lung- isolering, trakeal intubering och bronkoalveolärt lavage också beskrivits.

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Immunologi Akut lungskada luftvägsinflammation Djurmodeller lungsköljning Lipopolysackarid neutrofiler Lung leverans Steril inflammation.
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