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Journal / Immunology and Infection / 在小鼠B淋巴细胞染色体畸变所PNA-FISH快速分析…
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Immunology and Infection

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JoVE Journal Immunology and Infection
在小鼠B淋巴细胞染色体畸变所PNA-FISH快速分析
Use of an Optical Trap for Study of Host-Pathogen Interactions for Dynamic Live Cell Imaging
Journal (Immunology and Infection)
Use of an Optical Trap for Study of Host-Pathogen Interactions for Dynamic Live Cell Imaging
Author Spotlight: Expanding the Scope of Multiplex Immunoassays for Lyme Borreliosis Diagnostics and Pathogen Research (Video) | JoVE
Journal (Immunology and Infection)
Author Spotlight: Expanding the Scope of Multiplex Immunoassays for Lyme Borreliosis Diagnostics and Pathogen Research (Video) | JoVE
 
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在小鼠B淋巴细胞染色体畸变所PNA-FISH快速分析

Article DOI: 10.3791/51806-v • 07:54 min • August 19th, 2014
August 19th, 2014 •
1, 1
1Department of Molecular Biology and Biochemistry, Rutgers, the State University of New Jersey

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DNA修复途径对于维持基因组的完整性，防止基因突变和癌症至关重要。该协议的目的是通过直接观察染色体畸变的量化基因组不稳定性在中期从原位杂交（FISH）对端粒DNA重复使用荧光小鼠B细胞的扩散。

Tags

免疫学，第90，基因组不稳定性，DNA修复，鼠标，中期扩展，鱼，原代培养物
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