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Journal / Biology / Injeções intravenosas em Neonatal Ratos
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Injeções intravenosas em Neonatal Ratos
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Injeções intravenosas em Neonatal Ratos

Article DOI: 10.3791/52037-v • 05:17 min • November 11th, 2014
November 11th, 2014 •
1, 2, 1
1Department of Neuroscience, Ohio State University, 2Center for Gene Therapy, Nationwide Children's Hospital Research Institute, Ohio State University

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Modelos animais de doença pediátrica pode experimentar início precoce e progressão da doença agressiva. Clinicamente entrega terapia relevantes para jovens modelos de mouse pode ser tecnicamente difícil. Este protocolo descreve um método de injecção intravenosa não-invasiva para a ratinhos recém-nascidos nos dois primeiros dias pós-natais de vida.

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Protocolo Básico Edição 93 injecção intravenosa administração sistémica recém-nascido o AAV a terapia genética cérebro medula espinal músculo veia temporais
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