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Journal / Biology / Intravenöse Injektionen in neugeborenen Mäusen
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Intravenöse Injektionen in neugeborenen Mäusen
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Intravenöse Injektionen in neugeborenen Mäusen

Article DOI: 10.3791/52037-v • 05:17 min • November 11th, 2014
November 11th, 2014 •
1, 2, 1
1Department of Neuroscience, Ohio State University, 2Center for Gene Therapy, Nationwide Children's Hospital Research Institute, Ohio State University

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Tiermodelle der pädiatrischen Erkrankung früh einsetzende und aggressiven Krankheitsprogression zu erleben. Klinisch relevante Therapieabgabe, junge Maus-Modellen kann technisch schwierig sein. Dieses Protokoll beschreibt eine nicht-invasive Methode zur intravenösen Injektion neugeborene Mäuse innerhalb der ersten zwei Tage nach der Geburt des Lebens.

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Basisprotokoll intravenöse Injektion systemische Verabreichung Neugeborenen AAV Gentherapie Gehirn Rückenmark Muskeln zeitliche Venen
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