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Journal / Bioengineering / Porøst silicium mikropartikler til levering af…
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Porøst silicium mikropartikler til levering af siRNA Therapeutics
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Porøst silicium mikropartikler til levering af siRNA Therapeutics

Article DOI: 10.3791/52075-v • 08:31 min • January 15th, 2015
January 15th, 2015 •
*1,2, *1,3, 1, 1,4, 1, 2, 1,5, 1,6
1Department of Nanomedicine, Houston Methodist Research Institute, 2MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 3Pediatrics Department of Union Hospital, Huazhong University of Science and Technology, 4CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience & Technology of China, 5Department of Medicine, Weill Cornell Medical College, 6Department of Cell and Developmental Biology, Weill Cornell Medical College
* These authors contributed equally

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Levering er stadig den største udfordring for den terapeutiske gennemførelse af små interfererende RNA (siRNA). Denne protokol indebærer anvendelse af en multifunktionel og biokompatibel siRNA levering platform bestående af arginin og polyethylenimin podet porøst silicium mikropartikler.

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Bioengineering porøst silicium siRNA Nanodelivery system cancerterapi transfektion polykation funktionalisering
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