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Journal / Bioengineering / 多孔硅微粒进行交付的siRNA治疗的
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Bioengineering

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JoVE Journal Bioengineering
多孔硅微粒进行交付的siRNA治疗的
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多孔硅微粒进行交付的siRNA治疗的

Article DOI: 10.3791/52075-v • 08:31 min • January 15th, 2015
January 15th, 2015 •
*1,2, *1,3, 1, 1,4, 1, 2, 1,5, 1,6
1Department of Nanomedicine, Houston Methodist Research Institute, 2MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 3Pediatrics Department of Union Hospital, Huazhong University of Science and Technology, 4CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience & Technology of China, 5Department of Medicine, Weill Cornell Medical College, 6Department of Cell and Developmental Biology, Weill Cornell Medical College
* These authors contributed equally

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递送仍然是治疗性的实施的小干扰RNA（siRNA）的主要挑战。该协议涉及使用多官能的和生物相容siRNA递送平台，其中包括精氨酸和聚乙烯亚胺接枝的多孔硅微粒。

Tags

生物工程，第95，多孔硅的siRNA，Nanodelivery系统，癌症治疗，转染，聚阳离子功能化
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