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Journal / Medicine / Ex vivo behandeling Reactie van primaire tumoren…
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JoVE Journal Medicine
Ex vivo behandeling Reactie van primaire tumoren en / of geassocieerde Metastasen voor preklinische en klinische ontwikkeling van Therapeutics
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Ex vivo behandeling Reactie van primaire tumoren en / of geassocieerde Metastasen voor preklinische en klinische ontwikkeling van Therapeutics

Article DOI: 10.3791/52157-v • 08:29 min • October 2nd, 2014
October 2nd, 2014 •
*1, *2, 3, 4, 5, 5, 2, 6
1Department of Pathology, Memorial Sloan Kettering Cancer Center, 2Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, 3Department of Radiology, Weill Cornell Medical College, 4Department of Medicine, Memorial Sloan Kettering Cancer Center, 5Department of Oncology, Memorial Sloan Kettering Cancer Center, 6Department of Surgery, Memorial Sloan Kettering Cancer Center
* These authors contributed equally

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Opgericht kanker cellijnen en xenograften hebben de steunpilaar van het onderzoek naar kanker in de afgelopen paar decennia. Echter, recente gegevens blijkt dat de therapeutische respons sterk wordt beïnvloed door de tumorcel micromilieu. Daarom hebben wij een ex vivo analyse van de primaire tumor specimens geneesmiddelontwikkeling doeleinden ontwikkeld.

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Biologie kanker , Behandeling respons gevoeligheid / Verzet de ontwikkeling van geneesmiddelen Patiënt tumoren preklinische en klinische
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