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Journal / Medicine / Menschen Dupuytren'sche
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Menschen Dupuytren'sche
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Menschen Dupuytren'sche

Article DOI: 10.3791/52534-v • 08:59 min • April 18th, 2015
April 18th, 2015 •
1, 2, 3, 4, 4,5, 1,6
1Department of Molecular Cell Biology, Cancer Genomics Centre and Centre for Biomedical Genetics, Leiden University Medical Center, 2Department of Orthopedic Surgery, Academic Medical Center, 3Department of Plastic, Reconstructive and Hand Surgery, Academic Medical Center, 4Department of Orthopedic Surgery, Mayo Clinic, 5Department of Biochemistry and Molecular Biology, Mayo Clinic, 6Department of Dermatology, Leiden University Medical Center

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Morbus Dupuytren (DD) ist ein fibroproliferative Erkrankung der Handfläche der Hand. Hier stellen wir ein Protokoll zur Kultur Resektionsproben aus DD in einem dreidimensionalen (3D) Kultur-System. Solche Kurzzeitkultur-System ermöglicht die Erhaltung der 3D-Struktur und molekularen Eigenschaften des fibrotischen Gewebe.

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Medizin Fibrose Morbus Dupuytren TGFß 3D Kultursystem Compound-Bildschirm der extrazellulären Matrix
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