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Humant Dupuytrens
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Humant Dupuytrens

Article DOI: 10.3791/52534-v • 08:59 min • April 18th, 2015
April 18th, 2015 •
1, 2, 3, 4, 4,5, 1,6
1Department of Molecular Cell Biology, Cancer Genomics Centre and Centre for Biomedical Genetics, Leiden University Medical Center, 2Department of Orthopedic Surgery, Academic Medical Center, 3Department of Plastic, Reconstructive and Hand Surgery, Academic Medical Center, 4Department of Orthopedic Surgery, Mayo Clinic, 5Department of Biochemistry and Molecular Biology, Mayo Clinic, 6Department of Dermatology, Leiden University Medical Center

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Dupuytrens sjukdom (DD) är en fibroproliferativa sjukdom i handflatan. Här presenterar vi ett protokoll till kultur resektion exemplar från DD i en tredimensionell (3D) odlingssystem. En sådan kortsiktig kultur systemet tillåter bevarandet av 3D-strukturen och molekylära egenskaper hos fibrotiska vävnaden.

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Medicin fibros Dupuytrens sjukdom TGF 3D odlingssystem förening skärm extracellulära matrix
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