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Sporing Drug-induced Endringer i Receptor Post-intern Trafficking etter Colocalizational Analysis
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Sporing Drug-induced Endringer i Receptor Post-intern Trafficking etter Colocalizational Analysis

Article DOI: 10.3791/52824-v • 07:48 min • July 3rd, 2015
July 3rd, 2015 •
1,2, 1,2,3
1Department of Anesthesiology and Perioperative Care, University of California Irvine, 2Department of Biomedical and Molecular Sciences, Queen's University, 3Department of Pharmacology, University of California Irvine

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Receptor trafficking modulerer signalering og cellenes respons på ligander og er, i seg selv, som reagerer på celle forhold, blant annet ligandindusert signalering. Her beskriver vi en kraftig og fleksibel teknikk for kvantitativt vurdere legemiddelindusert reseptor trafficking ved hjelp immunolabeling og colocalizational analyse.

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Molecular Biology Trafficking Receptor G-protein koblet reseptor Intern Nedbrytning Gjenvinning colocalization Immunocytochemistry Immunhistokjemi Mikroskopi
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