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相关光学和电子显微镜,研究与β淀粉样蛋白斑块的小神经胶质互动
 
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相关光学和电子显微镜,研究与β淀粉样蛋白斑块的小神经胶质互动

Article DOI: 10.3791/54060-v 10:52 min June 1st, 2016
June 1st, 2016

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Summary

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本文介绍了使用甲氧基X04,它穿过血 - 脑屏障,并选择性地结合β褶的致密核心斑块Aβ发现张在阿尔茨海默氏症小鼠模型可视化淀粉样蛋白斑块Aβ的协议。它允许的前免疫染色和处理电子显微镜含斑块组织切片预检。

Tags

神经科学,第112,阿尔茨海默氏病,小鼠模型中,β淀粉样蛋白,小胶质细胞,免疫组织化学,荧光显微镜,电子显微镜
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