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Opsporen van Anastasis In Vivo door CaspaseTracker Biosensor

Article DOI: 10.3791/54107-v • 20:16 min • February 1st, 2018
February 1st, 2018 •
1,2, 2, 3
1Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, 2School of Life Sciences, Chinese University of Hong Kong, 3Department of Neurosurgery, Johns Hopkins University School of Medicine

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Anastasis is technisch uitdagende te detecteren in vivo omdat de cellen die de cel dood proces hebben omgekeerd morfologisch niet te onderscheiden van normale gezonde cellen kunnen. Hier beschrijven we protocollen voor het opsporen en volgen van cellen die anastasis in levende dieren ondergaan met behulp van ons nieuw ontwikkelde in vivo CaspaseTracker biosensor systeem.

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Geneeskunde kwestie 132 Anastasis apoptosis autophagy biosensor caspase CaspaseTracker necrose necroptosis geprogrammeerde celdood omkering van apoptosis
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