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Nefrotoxina microinjeção no peixe-zebra ao modelo de lesão renal aguda
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Nefrotoxina microinjeção no peixe-zebra ao modelo de lesão renal aguda

Article DOI: 10.3791/54241-v • 07:58 min • July 17th, 2016
July 17th, 2016 •
1,2, 1,2
1Center for Zebrafish Research, Department of Biological Sciences, University of Notre Dame, 2Center for Stem Cells and Regenerative Medicine, Department of Biological Sciences, University of Notre Dame

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lesões renais decorrentes de nefrotoxinas, que incluem drogas que variam de antibióticos para quimioterápicos, pode resultar em doenças complexas, cuja patogênese permanece incompletamente compreendida. Este protocolo demonstra como peixe-zebra pode ser utilizado para modelar doenças destas condições, que podem ser aplicados para a identificação de medidas renoprotetor.

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Medicina Edição 113 peixe-zebra rim nefrotoxina a depuração renal lesão renal aguda microinjecção gentamicina
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