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An Innovative Running Wheel-based Mechanism for Improved Rat Training Performance

Article DOI: 10.3791/54354-v • 07:51 min • September 19th, 2016
September 19th, 2016 •
1, 2, 3,4
1Department of Electronic Engineering, National Chin-Yi University of Technology, 2Department of Electrical Engineering, National Cheng Kung University, 3Department of Biotechnology, Southern Taiwan University of Science and Technology, 4Department of Medical Research, Chi Mei Medical Center

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Summary
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This study presents an innovative running wheel-based animal mobility system to quantify an effective exercise activity in rats. A rat-friendly testbed is built, using a predefined adaptive acceleration curve, and a high correlation between the effective exercise rate and the infarct volume suggests the protocol's potential for stroke prevention experiments.

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Running Wheel-based Mechanism Improved Rat Training Performance Exercise Activity Ischemic Stroke Prevention Small Medicine Field Effective Running Wheel System PRW System Traditional Treadmill System Stroke Prevention Effectiveness Middle Cerebral Artery Encroaching Results Disease Models Alzheimer's Disease Transparent Acrylic Running Wheel High-friction Rubber Track Iron Rod With Bearings Support Frame Semi-circular Transparent Acrylic Sheet
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