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Neuroscience

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In Vitro Recording of Mesenteric Afferent Nerve Activity in Mouse Jejunal and Colonic Segments
 

In Vitro Recording of Mesenteric Afferent Nerve Activity in Mouse Jejunal and Colonic Segments

Article DOI: 10.3791/54576-v 10:32 min October 25th, 2016
October 25th, 2016

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Summary

Mesenteric afferent nerves convey information from the gastrointestinal tract towards the brain regarding normal homeostasis as well as pathophysiology. Gastrointestinal afferent nerve activity can be assessed by mounting isolated intestinal segments with attached afferent nerves into an organ bath, isolating the nerve, and assessing basal as well as stimulated activity.

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In Vitro Recording Mesenteric Afferent Nerve Activity Mouse Jejunal Colonic Segments Neuroscience Disease States Nerve Discharge Recording Nerve Sensitization Irritable Bowel Syndrome Pain Syndromes Single Unit Analysis Abdominal Midline Incision Krebs Solution Jejunum Excision
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