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Journal / Medicine / Metod för Direct segment Intra-lever Delivery…
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Medicine

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JoVE Journal Medicine
Metod för Direct segment Intra-lever Delivery hjälp av en råttlever hilar Clamp Modell
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Metod för Direct segment Intra-lever Delivery hjälp av en råttlever hilar Clamp Modell

Article DOI: 10.3791/54729-v • 09:22 min • April 2nd, 2017
April 2nd, 2017 •
1, 1, 1, 1, 1, 1, 1, 1
1Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Lab, Division of Transplant, Department of Surgery, Comprehensive Transplant Center, The Ohio State University Wexner Medical Center

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En unik råttlever hilar klämma modell utvecklades för att studera effekterna av farmakologiska molekyler vid lindring av ischemi-reperfusionsskada. Denna modell inkluderar direkt kanylering av portalen tillförseln till ischemisk leversegmentet via en gren av portalvenen, vilket möjliggör direkt leverleverans.

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Medicin hilar klämma ischemi-reperfusionsskada levertransplantation polyetylenglykol-superoxiddismutas (PEG-SOD) råtta direkt kanylering hepatisk leverans
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